Welcome to the Yang Lab at UFCD
|
The Yang Lab at UFCD (University of Florida College of Dentistry) is dedicated to unraveling the mechanism of bone turnover and tooth movement, hoping to provide patients with better treatment.
|
Alveolar Bone RemodelingWe have been using animal models with orthodontic tooth movement to explore the mechanism during alveolar bone remodeling in vivo.
We also conduct in vitro cell cultures with mechanical forces mimicking bone remodeling to investigate its biological mechanism. |
Craniofacial Bone RegenerationCollaborating with biomaterial labs, we are testing the effectiveness and efficiency of novel biomaterials for promoting craniofacial bone regeneration by using animal models with craniofacial bone defects. Moreover, we also explore the biological mechanism of biomaterials and biomolecules in regulating osteogenic differentiation of stromal cells.
|
Translational and Clinical Research
Working with patients, we carry out some clinical trials, as well as perform sequencing and mass spec to analyze the difference in the transcriptome, proteome, and PTMome between the experimental and control groups to understand the chemical biological change happening within the progress of diseases, which will help to provide patients with better treatment in the future.
|
